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From my point of view, if the difference between what about and how about in general is slight, the difference between what about you and how about you is even slighter. They are certainly interchangeable, as you mentioned, but I would go so far as to say that their common usages are semantically indistinguishable. In point of usage, Ngrams shows a slight preference for What about you: COCA ...
Use of "what" vs "that" - English Language & Usage Stack Exchange